Jose Mourinho was condemned to his first defeat since arriving Tottenham and interestingly it was his former club who did the damage.
The Portuguese made his first return to Old Trafford since his sack in December 2018, with high hopes of sustaining his winning streak to four.
That dream was shattered as Manchester United players raised their game against their former boss, with Rashford opening scoring in the first 7 minutes of play to put United in front.
United created several other chances but failed to convert them to goal until Dele Ali struck in the 39 minutes to level up for Spurs and rekindled their hope of salvaging a point.
In the 49minutes Rashford converted a spot kick to seal victory for United, giving Jose Mourinho his first defeat since arrival at Spurs.
The loss means Mourinho’s Tottenham remain 8 position on the table after 15 games, while United climb up to sixth on the table.